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Fig. 6 Effects of chemicals on lymphangiogenesis can be examined by monitoring expression of lyve1. A-C: Specification of lymphatic progenitors was not affected by lyve1 MO (A), but by prox1 MO (B,C), in 26 hpf embryos; blood vessel formation was unaltered (C). D-I: vegfc MO or 400 nM rapamycin reduced lymphatic budding and sprouting in 54 hpf embryos. J-L: Blood vessels remained normal in control and test embryos. All lateral views, except for D-F, which are dorsal views. TD, thoracic duct.
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