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Fig. S7 Syk and Zap morphants lack a thoracic duct. Angiography in wild type Tg(fli1a:EGFP)y1 embryos shows a clear separation between the dorsal aorta and posterior cardinal vein, and the presence of the thoracic duct lacking dye between the two vessels (A, A′). Conversely, angiography in sykLO (B, B′), zap-70LO (C, C′), and sykLO:zap-70LO double morphants (D, D′) demonstrates the clear lack of a thoracic duct between the artery and vein. In sykLO:zap-70LO double morphants, some ISVs also appear to have restricted or lack blood flow.
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Reprinted from Developmental Biology, 340(1), Christie, T.L., Carter, A., Rollins, E.L., and Childs, S.J., Syk and Zap-70 function redundantly to promote angioblast migration, 22-29, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.