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Fig. 2 BBSome is not formed in Bbs6 null mouse tissues. (A) Wild-type (WT) and Bbs6 null (6KO) mouse testis extracts were fractionated by size exclusion chromatography. Elution fractions were subjected to SDS/PAGE and immunoblotting. Membranes were probed with antibodies against Bbs1, Bbs2, Bbs4, Bbs7, and Bbs8. (B) Extracts from wild-type and Bbs6 null eye were analyzed as in A. Open arrowhead indicates Bbs1; closed arrowhead indicates a cross-reacting protein. It should be noted that Bbs1 blot from Bbs6 null eye was exposed longer than that of wild-type.
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Full text @ Proc. Natl. Acad. Sci. USA