ZFIN Image: Schütte et al., 2010, Fig. 3

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Figure Caption

Fig. 3 The vascular system of meprin α₂ knockdown embryos exhibits dramatic defects (B, C).

Microangiography (with TRITC-Dextran) revealed a drastically reduced vascular system without any intersegmental blood vessels (B) in meprin α₂ morphants, compared to the non-injected wild type zebrafish (A). Additionally, erythrocytes accumulated in the ventral caudal tail region (C), possibly as a consequence of this sprouting failure. (PCeV: Posterior cerebral vein; ISV: intersegmental vessels; DLAV: dorsal longitudinal anastomotic vessel; CA: caudal artery; DA: dorsal aorta CV: caudal vein; PCV: posterior cardinal vein; L: liver; H: heart) (Scale bar: 250 μm).

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Acknowledgments

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