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Fig. 1 Accumulation of anosmin-1a in the olfactory system. (A–C) Frontal view with dorsal region to the top; (D) dorsal view with anterior to the left. Whole-mount immunodetection of anosmin-1a in a 36 (A) and 72 hpf (B–D) embryos. Arrows indicate immuno-reactive OSN axons, which have entered olfactory bulbs. Double-headed arrows indicate the dorso-ventral (D-V) and antero-posterior (A-P) axes. OB, olfactory bulb; OE, olfactory epithelium; n, nostril. Scale bar = 150 μm in A and D, 100 μm in B, and 30 μm in C.
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Reprinted from Molecular and Cellular Endocrinology, 312(1-2), Yanicostas, C., Herbomel, E., Dipietromaria, A., and Soussi-Yanicostas, N., Anosmin-1a is required for fasciculation and terminal targeting of olfactory sensory neuron axons in the zebrafish olfactory system, 53-60, Copyright (2009) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.