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Fig. S8 Endodermal development following SU5402 treatment from 24–28 hpf. Lateral views, anterior to the left. (A,B) tg{fli1::eGFP} (green) embryo marking postmigratory CNCCs double labeled with the endoderm marker Zn-8 (red). (A) Control embryo treated from 24–28 hpf with DMSO shows normal arch and pharyngeal pouch development. (B) Embryo treated with SU5402 from 24–28 hpf shows reduced arches 3 and 4, as well as broad and less elongated posterior pharyngeal pouches as compared to DMSO treated control sibling.
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Reprinted from Developmental Biology, 333(1), Olesnicky Killian, E.C., Birkholz, D.A., and Artinger, K.B., A role for chemokine signaling in neural crest cell migration and craniofacial development, 161-172, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.