ZFIN Image: Sun et al., 2009, Fig. 3

Image

Figure Caption

Fig. 3 Myocyte hypertrophy contributes to early stages of cardiac remodeling in tr265/tr265.

(A–B′) Images of cardiomyocytes (red⁺ blue⁺; arrow) and non-cardiomyocytes (blue⁺ only; arrowhead) in week-6 and -16 (A, B) sibling and (A′,B′) tr265/tr265 ventricle sections from fish outcrossed to Tg(cmlc2:nuDsRed) fish, whose terminally-differentiated cardiomyocyte nuclei are fluorescent red; blue is Hoechst-labeling of nuclei; bar = 10 μm. (C–D′) Dissociated ventricular cardiomyocytes cultured and imaged to reveal cell size and shape from week-6 and-16 (C,D) sibling and (C′,D′) tr265/tr265 fish; bar = 20 μm. (E) Cardiomyocyte and (F) non-cardiomyocyte density (cells/mm²) from fish represented in A–B′. (G) Surface area (in μm²) of cultured cardiomyocytes, like the ones in C–D′. (E–G) mean±SEM; * = P<0.05. n = number of fish examined.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One