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Fig. S2
Tg(hsp70:alk8) Rescues Zygotic laf Mutants during Early Somitogenesis
Non-heat-shocked live laf mutant embryo displays a class 2 (C2) dorsalized phenotype indicated by complete loss of the ventral tail fin and ventral tail vein at 48 hpf (A). Heat-shocked transgenic laf embryos rescued to wild-type (B), weak C1 (less than 50% of the tail fin missing) (C), or strong C1 (more than 50% of the tail fin missing) (D) phenotype. Arrows denote extent of missing ventral tail fin.
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Reprinted from Developmental Cell, 14(1), Tucker, J.A., Mintzer, K.A., and Mullins, M.C., The BMP signaling gradient patterns dorsoventral tissues in a temporally progressive manner along the anteroposterior axis, 108-119, Copyright (2008) with permission from Elsevier. Full text @ Dev. Cell