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Fig. 1 Formation of the BMP Activity Gradient
Whole-mount P-Smad5 (green) antibody staining during blastula stages, at 4 hpf (A), 4.75 hpf (B), and 5 hpf (C) and during gastrula stages at 5.5 hpf (D), 6 hpf (E), 6.25 hpf (F), 7.25 hpf (G), 8.25 hpf (H), and 9 hpf (I). Nuclei were stained with DAPI (blue). (A)–(E) Animal view. (F)–(I) Lateral view. Dorsal to right in all.
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Reprinted from Developmental Cell, 14(1), Tucker, J.A., Mintzer, K.A., and Mullins, M.C., The BMP signaling gradient patterns dorsoventral tissues in a temporally progressive manner along the anteroposterior axis, 108-119, Copyright (2008) with permission from Elsevier. Full text @ Dev. Cell