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Fig. 6 The cloche (clom39) and spadetail (sptb104) mutations affect definitive progenitors in the dorsal aorta. Whole-mount in situ hybridization of 48-h-old wild-type (A, D), clom39 (B, E), and sptb104 (C) embryos with c-myb (A–C) and flk1 (D, E). All three mutations greatly reduce the number of cells that express c-myb in the dorsal aortas of 48-h-old embryos (arrows A–C). Cells expressing flk1 are seen in the tails of 48-h-old embryos (arrows D, E).
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Reprinted from Developmental Biology, 197, Thompson, M.A., Ransom, D.G., Pratt, S.J., MacLennan, H., Kieran, M.W., Detrich,III, H.W., Vail, B., Huber, T.L., Paw, B., Brownlie, A.J., Oates, A.C., Fritz, A., Gates, MA., Amores, A., Bahary, N., Talbot, W.S., Her, H., Beier, D.R., Postlethwait, J.H., and Zon, L.I., The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis, 248-269, Copyright (1998) with permission from Elsevier. Full text @ Dev. Biol.