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Fig. S2 Zebrafish transgenic line Tg(shh::EGFP) (Shkumatava et al., 2004) was used to observe the fin-bud development. The white arrow indicates the fin-bud of wild-type (WT) (A,B). When we injected arl6ip-MO1 (MO) into embryos derived from this line and observed at 52 hpf by confocal microscopy, we found that the fin-bud development was defective (C,D). Embryos were photographed under blue light (A,C) and bright field overlapped with blue light (B,D). The scale bar = 250 μm.
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