ZFIN Image: Esterberg et al., 2009, Fig. S3

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Figure Caption

Fig. S3 FGF activity is not compromised in Dlx3b/4b morphant embryos prior to the onset of somitogenesis. Bud stage embryos stained with riboprobes against erm, fgfr1, fgfr2, fgfr3, or fgfr4 show that expression is unchanged in Dlx3b/4b morphant embryos (B,D,F,H,J) when compared to controls (A,C,E,G,I). The arrow represents the otic placode. The arrowhead represents the notochord. The asterisk marks a region bordering the neural plate anterior to the otic placode. MHB, midbrain–hindbrain boundary; hb, hindbrain; r2, rhombomere 2; psm, presomitic mesoderm. (A–J) Bud stage embryos; dorsal views with anterior to the top.

Acknowledgments

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Reprinted from Developmental Biology, 325(1), Esterberg, R., and Fritz, A., dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity, 189-199, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.