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Fig. 6 Ectopic dlx3b or cv2 expression can induce ectopic FGF activity. (A–C) Ectopic dlx3b expression (red) can induce ectopic expression of erm, spry4, and fgfr1 (purple). (D–F) Ectopic cv2 expression (red) can induce ectopic expression of erm, spry4, and fgfr1 (purple). (G–I) All cells ectopically expressing the uncleavable form of Cv2, cv2-CM (red), ectopically express erm, spry4, and fgfr1 (purple). (A–I) 80% epiboly embryos; lateral views.
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Reprinted from Developmental Biology, 325(1), Esterberg, R., and Fritz, A., dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity, 189-199, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.