ZFIN Image: Osborne et al., 2008, Fig. 1

Image

Figure Caption

Fig. 1 two of hearts and miles apart Mutant Phenotypes

Comparison of WT (A–C), toh mutant (D–F), and mil/s1p2 mutant (G–I) embryos.

(A, D, and G) Lateral brightfield images, anterior to the left, at 36 hpf show pericardial edema (arrow) and epidermal blisters (insets, arrowheads) in the tails of toh^sk12 (D) and mil/s1p2^m93 (G) mutants.

(B, E and H) Examination of cmlc2 expression at 19 hpf shows heart-ring formation in WT embryos (B) and a failure in precardiac-mesoderm migration in toh^s420 (E) and mil/s1p2^m93 (H) mutant embryos. Dorsal views with anterior upwards.

(C, F and I) Visualization of the anterior endoderm by Tg(-0.7her5:EGFP)^ne2067 expression at 18 hpf. In embryos injected with toh (F) and mil/s1p2 (I) MOs, numerous gaps (arrowheads) appear in the endodermal sheet, which is also irregularly shaped. The most anterior region of mil/s1p2 morphants lacks GFP⁺ endodermal cells at the midline (asterisk). Dorsal views with anterior upwards.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Curr. Biol.