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Fig. S3 Maternal Zygotic (MZ) pard6γbs441 mutant embryos. (A, A′) 36 hpf MZpard6γbs441 mutant embryo. (A) The overall body phenotype of maternal zygotic mutant embryos is similar to zygotic mutants. (A′) The retinal pigmented epithelium is more severely affected in maternal zygotic mutants. (B) A MZpard6γbs441 mutant embryo sectioned between the first and sixth somite and stained for ZO-1 (blue), aPKC (red), and filamentous actin (green) at 30 hpf. MZpard6γbs441 mutant embryos show a multiple lumen phenotype similar to that seen in zygotic pard6γbs441 mutants.
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Reprinted from Developmental Biology, 324(1), Munson, C., Huisken, J., Bit-Avragim, N., Kuo, T., Dong, P.D., Ober, E.A., Verkade, H., Abdelilah-Seyfried, S., and Stainier, D.Y., Regulation of neurocoel morphogenesis by Pard6gammab, 41-54, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.