Fig. 9
Fig. 9. C1q-like is essential for defense and survival in response to bacterial infection. (A) C1q-like expression changes detected by Q-RT-PCR at different times after the embryos infected by the pathogen bacterium Aeromonas hydrophila at 24 hpf. The ratio of C1q-like to β-actin in untreated embryos was set to 1 in every stage, and all infected embryos were normalized relative to this value. The data represent mean ± SD of three separate experiments. Hpi means hours post infection. (B) At 24 hpf, the normal control wild-type embryos, the over-expressed C1q-like embryos, and the C1q-like morphant embryos were respectively challenged with the pathogen bacterium Aeromonas hydrophila, and the cumulative mortality were recorded at the indicated times after infection. The data represents mean ± SD of three separate experiments. p < 0.05.
Reprinted from Developmental Biology, 319(2), Mei, J., Zhang, Q.Y., Li, Z., Lin, S., and Gui, J.F., C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis, 273-284, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.