ZFIN Image: Clay et al., 2008, Fig. S4

Image

Figure Caption

Fig. S4 Macrophage death can lead to dissemination of infection.
All images are stills taken from a two hour timelapse of an infected TR1 morphant fish at four dpi. A single dead infected macrophage is rephagocytosed by two separate macrophages. When available, flattened three-dimensional fluorescent stacks are provided to indicate position of bacteria (left column). Time is shown in minutes. The original macrophage is indicated by left-facing bracket, first incoming macrophage is indicated by upward-facing bracket, and second incoming macrophage is indicated by right-facing bracket. Scale bar, 10 μm.

Acknowledgments

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Reprinted from Immunity, 29(2), Clay, H., Volkman, H.E., and Ramakrishnan, L., Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death, 283-294, Copyright (2008) with permission from Elsevier. Full text @ Immunity