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Fig. 8 C1q-like MO affects the hematopoiesis and brain blood vessel organization. (A) The embryo phenotypes stained by O-dianisidine at 48 hpf. The embryos are shown as lateral views (a, c, e) and ventral views. (B) The effect of C1q-like MO on brain (a, b, c) and tail (d, e, f) blood vessels in the flk-1:GFP-transgenic zebrafish. The blood vessels of embryos were imaged at 48 hpf at 10x. Arrows show the mesencephalic vein (MsV). Each picture represents typical results from three experiments (more than 20 embryos in each experiment).
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Reprinted from Developmental Biology, 319(2), Mei, J., Zhang, Q.Y., Li, Z., Lin, S., and Gui, J.F., C1q-like inhibits p53-mediated apoptosis and controls normal hematopoiesis during zebrafish embryogenesis, 273-284, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.