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Fig. 6 ENS NCC fail to migrate from the vagal region to the anterior end of the intestine in 24–36 hpf cyclopamine treated embryos. (A, B) Ventral view of the anterior end of the intestine in 36 hpf wildtype (A) and 24–36 hpf cyclopamine treated (B) embryos that have been hybridized with an antisense probe to crestin. Arrows indicate migrating ENS NCC. Anterior is to the left.
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Reprinted from Developmental Biology, 318(1), Reichenbach, B., Delalande, J.M., Kolmogorova, E., Prier, A., Nguyen, T., Smith, C.M., Holzschuh, J., and Shepherd, I.T., Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish, 52-64, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.