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Fig. 2

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ZDB-IMAGE-080522-27
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Figures for Filippi et al., 2005
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Fig. 2 olig3 controls specification of the neural crest. (ad) The levels and the expression domains of sox10 and foxd3 are decreased in four-somite embryos injected with olig3 mRNA (b and d) (phenotype in >90% of injected embryos, n = 30). (e and f) The expression of foxd3 is increased in 15-somite embryos treated with olig3MO (f) (morphant phenotype > 90%, n = 20). Similarly, the expression of crestin is increased in 30-hpf embryos treated with olig3MO (h and f) (morphant phenotype > 90%, n = 40). Similar results are obtained in 24-hpf embryos hybridized with sox10 (k and l) (morphant phenotype > 90%, n = 30). Embryos are in dorsal (ah, k, and l) or lateral (i and j) view, anterior to the top (ad) or to the left (el).

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