ZFIN Image: Park et al., 2002, Fig. 6

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Figure Caption

Fig. 6 olig2 promotes oligodendrocyte development. (A, B) Transverse sections through trunk spinal cord (sc) of 48-hpf embryos hybridized with sox10 RNA probe. Brackets indicate ventral spinal cord and arrows point to sox10 expression in lateral line. Spinal cord expression of sox10 was absent from embryo injected with olig2 MO, whereas lateral line expression was normal (B). (C-E) Transverse sections of 72-hpf embryos hybridized with dm20/plp RNA probe. Arrows indicate dm20/plp-expressing oligodendrocytes. Embryos injected with olig2 MO did not express dm20/plp (D), whereas those injected with olig2 mRNA had a small but significant increase in the number of dm20/plp-expressing cells (E) (see Table 1). Scale bar, 20 μm.

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Acknowledgments

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Reprinted from Developmental Biology, 248(2), Park, H.-C., Mehta, A., Richardson, J.S., and Appel, B., olig2 is required for zebrafish primary motor neuron and oligodendrocyte development, 356-368, Copyright (2002) with permission from Elsevier. Full text @ Dev. Biol.