Fig. 4 Effects of cytochalasin B and latrunculin A on VAMP-2 immunofluorescence. Panel A illustrates the extent of VAMP-2 immunofluorescence labeling of the furrow region in representative control embryos during late deepening and full apposition (see arrowheads in panels Ai and Aii, respectively). Panels B (i and ii) and C (i and ii) show VAMP-2 labeling (see arrowheads) in embryos treated with 10.4 μM cytochalasin B and 2 μM latrunculin A, respectively, at equivalent time periods as the controls. In both these cases the cleavage furrows are either in the process of regressing (see panels Bi and Ci) or are fully regressed (see panels Bii and Cii).
Reprinted from Developmental Biology, 316(2), Li, W.M., Webb, S.E., Chan, C.M., and Miller, A.L., Multiple roles of the furrow deepening Ca2+ transient during cytokinesis in zebrafish embryos, 228-248, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.