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Fig. S2 isl1 and meis3 knockdown reduces the exocrine tissue. Embryos were injected with isl1 or meis3 morpholino (MO) and the expression of the exocrine marker trypsin (try) was analyzed by in situ hybridization at 76 hpf. Ventral views, anterior to the left and left side to the top. (A) Control embryos injected with a control morpholino (meis3 MO with five mismatches or unrelated MO). (B) Representative embryo injected with isl1 MO out of the 88% injected embryos exhibiting defects (n=158) (top), and injected with meis3 MO out of the 95% embryos (n=203) (bottom).
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