ZFIN Image: Stickney et al., 2007, Fig. 5

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Figure Caption

Fig. 5 Blood fate is first expanded and then reduced upon progressive loss of BMP activity. gata1 expression at 10 somites in embryos from a cross between a triple bmp heterozygote and a bmp4^st72 heterozygote. (A) Wild-type phenotype exhibited by a bmp4^st72 heterozygote. Expansion of the gata1 expression domain ventral to the tailbud is evident in a bmp4^st72 homozygote (B) and a bmp4^st72/bmp4^st72; snh^ty68a/+ embryo (C). Reduction of the gata1 expression domain is observed upon further reduction of BMP, as in these bmp4^st72/bmp4^st72; swr^ta72/+ (D) and bmp4^st72/bmp4^st72; snh^ty68a/+; swr^ta72/+ (E) embryos, although ectopic gata1 expression ventral to the tailbud is still apparent.

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Acknowledgments

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Reprinted from Developmental Biology, 310(1), Stickney, H.L., Imai, Y., Draper, B., Moens, C. and Talbot, W.S., Zebrafish bmp4 functions during late gastrulation to specify ventroposterior cell fates, 71-84, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.