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Fig. 9 Morphology of the PP2-treated embryos. Fertilized eggs (3 min postinsemination) were treated with 4 μM PP2, or PP3 as a control for 5 h. Embryos resulting from eggs treated with PP2 exhibited normal morphology at the high/sphere stage (a) but they exhibited a range of defects involving failure of epiboly (b). Embryos treated with PP3 exhibited normal development (c–d).
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Reprinted from Developmental Biology, 277(1), Tsai, W.B., Zhang, X., Sharma, D., Wu, W., and Kinsey, W.H., Role of Yes kinase during early zebrafish development, 129-141, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.