IMAGE

Fig. S5

ID

ZDB-IMAGE-071005-11

Genes

Source

Figures for Walker et al., 2006

Image

Figure Caption

Fig. S5 furinA and furinB redundantly activate dlx5a, hand2, and stimulate ventral arch elongation. (A–D) hand2 expression at 55 hpf is dramatically reduced in furinA⁻;furinB MO (D) embryos with respect to WT (A), furinA⁻ (B), and furinB MO (C) embryos. (E–H) dlx5a expression at 36 hpf is strongly reduced in furinA⁻;furinB MO (H) embryos with respect to WT (E), furinA⁻ (F), and furinB MO (G) embryos. (I–L) dlx2a staining at 36 hpf illustrates the arch length. Ventral arch length below the first pouch is substantially reduced in furinA⁻;furinB MO embryos (L) with respect to WT (I), furinA⁻ (J), and furinB MO (K) embryos. a1 and a2 label pharyngeal arch 1 and 2. Dotted lines label pouch 1. m labels the mouth; eye labels the eye. Scale bars: 50 μm.

Figure Data

Expression / Labeling details

Acknowledgments

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Reprinted from Developmental Biology, 295(1), Walker, M.B., Miller, C.T., Talbot, J.C., Stock, D.W., and Kimmel, C.B., Zebrafish furin mutants reveal intricacies in regulating Endothelin1 signaling in craniofacial patterning, 194-205, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.