ZFIN Image: Varga et al., 2007, Fig. 5

Image

Figure Caption

Fig. 5 Germ-ring expression of chordin is repressed by Wnt8 through the transcriptional repressors Vox and Vent. ich embryos co-injected with MOs targeted against both ORFs of wnt8 (B) or with MOs against both vox and vent (D) show ectopic expression of chd around the germ-ring. Uninjected ich embryos do not express chd (A and C). Suppression of β-catenin signaling in the germ-ring of ich embryos by injection of βcat1MO + βcat2MO (MO1 + MO2) causes a decrease of vox and vent expression (compare E with F, and G with H). Embryos are shown in lateral (A–D) or animal (E–H) views at 70% epiboly. Concentrations of MOs injected were 0.6 mM of each of the two Wnt8MOs, 0.7 mM of each of voxMO and ventMO, and 3 mM of each of the two β-catenin MOs.

Figure Data

Expression / Labeling details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Mechanisms of Development, 124(9-10), Varga, M., Maegawa, S., Bellipanni, G., and Weinberg, E.S., Chordin expression, mediated by Nodal and FGF signaling, is restricted by redundant function of two beta-catenins in the zebrafish embryo, 775-791, Copyright (2007) with permission from Elsevier. Full text @ Mech. Dev.