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Fig. 10 furinA and edn1 mutants have an early defect in ventral arch elongation. Bottom of pharyngeal pouch 1 (p1) to yolk distance was measured in micrometers. Each data point represents measurements from 5 embryos, with error bars representing standard error. edn1 mutants have a strong defect in ventral arch elongation from 24 to 30 hpf. furinA mutants have a moderate defect in ventral arch elongation from 24 to 30 hpf. The ventral arch elongation defects recover significantly in furinA and edn1 mutants between 30 and 36 hpf.
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Reprinted from Developmental Biology, 295(1), Walker, M.B., Miller, C.T., Talbot, J.C., Stock, D.W., and Kimmel, C.B., Zebrafish furin mutants reveal intricacies in regulating Endothelin1 signaling in craniofacial patterning, 194-205, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.