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Fig. 4 optcl is expressed in the CNS, lens and somites: (A) a ventral view showing that optcl is expressed in the somites (arrows) including the adaxial cells (arrowheads) in 12 hpf embryos; (B) a lateral view showing that at 16 hpf optcl expression is detected in the eye vesicles, MHB (arrow), and floor plate cells (arrowheads). optcl is also strongly expressed in somites at this stage; (C) lateral view of a 24 hpf embryo showing that optcl is expressed by the eye, MHB, and floor plate but optcl has decreased in the somites; (D) dorsal view of the head of a 25 hpf embryo showing that optcl is highly expressed in the lens (L) and the MHB (arrows). Cells surrounding the olfactory placode (OP) express optcl at a relatively low level; (E) dorsal view of hindbrain and anterior spinal cord at 25 hpf showing optcl expression in the floor plate of the hindbrain and spinal cord along with some expression in the somites; (F) a transverse section through the trunk of 24 hpf embryo showing that optcl is expressed in the floor plate of spinal cord (black arrow), hypercord (arrowhead), muscle pioneer cells (red arrowhead) and the superficial slow twitch muscles; (G) at 48 hpf optcl is expressed by the superficial cells of the lens (L) and (H) the floor plate of spinal cord (arrows, lateral view).
Reprinted from Gene expression patterns : GEP, 6(5), Zhou, W., Shirabe, K., and Kuwada, J.Y., Molecular cloning and expression of two small leucine-rich proteoglycan (SLRP) genes, dspg3l and optcl, in zebrafish, 482-488, Copyright (2006) with permission from Elsevier. Full text @ Gene Expr. Patterns