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Fig. 5 MO knockdown: pigment cell differentiation markers, in situ hybridizations. (A) Histogram of tail iridophore counts. Both MOs were injected at 2 mg/ml. The mean number of tail iridophores per embryo ± SEM are depicted for uninjected (n = 60), morpholino injected (n = 107), and mismatch morpholino injected (n = 83). (B) Presumptive iridophores expressing ednrb1 (endothelin receptor b1) are absent from Foxd3 morpholino-injected embryos. (C) Melanoblast marker dct (dopachrome tautomerase) is unaffected. (D) Xanthoblast marker xdh (xanthine dehydrogenase) is slightly reduced in the trunk.
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Reprinted from Developmental Biology, 290(1), Lister, J.A., Cooper, C., Nguyen, K., Modrell, M., Grant, K., and Raible, D.W., Zebrafish Foxd3 is required for development of a subset of neural crest derivatives, 92-104, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.