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Fig. 4 Morphology of pectoral fin buds of fibin knockdown embryos. (A) Embryos were injected with antisense five-base mismatched fibin MO (Control) and fibin MO. The morphology in wild-type (a, b), control (c, d) and fibin knockdown (e, f) embryos was observed at 4 dpf. Arrowheads and asterisks indicate pectoral fins and no pectoral fins, respectively. (B) The morphology of pectoral fin buds was observed in wild-type (a, d, g), control (b, e, h) and fibin knockdown (c, f, i) embryos at 32∼48 hpf.
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Reprinted from Developmental Biology, 303(2), Wakahara, T., Kusu, N., Yamauchi, H., Kimura, I., Konishi, M., Miyake, A., and Itoh, N., fibin, a novel secreted lateral plate mesoderm signal, is essential for pectoral fin bud initiation in zebrafish, 527-535, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.