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Fig. S4 Development and differentiation of the forebrain is not abolished in chks399 mutant fish. Gene expression in chks399 (chokh) fish vs. sibling (wt). Stages and probes as indicated. Views: (A,B,E,F,I-P) lateral, anterior to the left. (C,D,G,H,Q-T) ventral, anterior to the left. Note that the early-born vtn cells that are not initiated in homozygous chk mutant fish are also absent at later stages (black arrows in A,B) with 100% penetrance. (compare to Fig. 6).

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Reprinted from Cell, 129(7), Tessmar-Raible, K., Raible, F., Christodoulou, F., Guy, K., Rembold, M., Hausen, H., and Arendt, D., Conserved sensory-neurosecretory cell types in annelid and fish forebrain: insights into hypothalamus evolution, 1389-1400, Copyright (2007) with permission from Elsevier. Full text @ Cell