ZFIN Image: Curado et al., 2007, Fig. S1

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Figure Caption

Fig. S1 Tissue-specific damage to the heart upon exposure of Tg(cmlc2:CFP-NTR)^s890 larvae to Mtz. Merged images and single channels of heart sections of Tg(cmlc2:CFP-NTR)^s890; Tg(cmlc2:GFP) larvae treated with DMSO- (A-A’’’- magnification of Fig. 2E) and Mtz- (B-B’’’ - same as Fig. 2G) immunostained for activated Caspase-3 in blue (A’, B’) and stained with rhodamine phalloidin in red (A’’, B’’), Tg(cmlc2:GFP) in green (A’’’, B’’’). Activated Caspase-3 expression (B’) was detected exclusively in Tg(cmlc2:GFP) expressing cells (B’’’) indicating that cell death occured specifically in cardiomyocytes and without affecting the neighboring CFP-NTR- cells.

Acknowledgments

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