ZFIN Image: Eroglu et al., 2006, Fig. 2

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Figure Caption

Fig. 2 Brg1 expression is critical in neurodevelopment and the proper formation of body axis. A,B: One- to two-cell-stage embryos were injected with control- (A, control) or Brg1-specific MOs (B, Brg1-MO) (10 ng/embryo). Embryos were photographed at 25 hpf. Original magnification 100×. C,D: Dorsal view showing mid/hind-brain boundary under normal conditions (C) or aberrant neural tube development in Brg1-MO-injected embryos at 25 hpf (D). Original magnification 100×. E,F: One- to two-stage embryos were injected with Acridine Orange. Embryos were injected with control-MO (I) or Brg1-MO (J) and photographed at 25 hpf. Morphant phenotypes were more than 90%, n = 30. G-J: Control-MO-injected or Brg1-MO-injected embryos at 48 hpf (E and F) and 4 dpf (G and H). Morphant phenotypes were more than 90%, n = 50. Original magnification 40×.

Acknowledgments

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