ZFIN Image: Won et al., 2006, Fig. 4

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Figure Caption

Fig. 4 Aberrant neuronal cell development in the absence of Delta-Notch signaling, or Ngn1. A: At 24 hours postfertilization (hpf), lateral view of wild-type embryo. Inset: High-magnification dorsal view of the spinal cord. B: 1G5z expression pattern in mib^ta52b mutant. Inset: High-magnification dorsal view of the spinal cord. C-F: At the 24 hpf. C: Dorsal view of uninjected control embryo. 1G5z transcripts are detected in trigeminal ganglion (asterisk) and anterior hindbrain (arrow). D: ngn1 mopholino (MO) -injected embryo. Note the complete lack of 1G5z expression in the trigeminal ganglion (asterisk) and anterior hindbrain (arrow). E,F: Lateral view of medial-caudal trunk of the same embryos of C and D. Note that ngn1 MO injection abolished 1G5z expression in the posterior sensory neuronal cells (arrowhead). Arrows indicate interneurons. IN, interneuron; SN, sensory neuron.

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Acknowledgments

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