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Fig. 10 Constant light rearing exacerbates cell death in dazed mutants. A: Wild-type (WT) retinas did not exhibit defects after constant light treatment. B: Retinas from dazed mutants raised under constant lighting displayed widespread cell death in all cell layers and large holes in the photoreceptor layer both centrally and peripherally. C: Wild-type retinas from animals raised in constant darkness appeared slightly developmentally delayed, but degeneration was not observed. D: Dark-reared dazed retinas degenerate. Pyknotic cells were found in the photoreceptor layer, and acellular holes were seen at the marginal zones as in animals raised under cyclic light. Scale bar = 70 μm in D (applies to A-D).