Gene
ctnna1
- ID
- ZDB-GENE-991207-24
- Name
- catenin (cadherin-associated protein), alpha 1
- Symbol
- ctnna1 Nomenclature History
- Previous Names
-
- ctnna
- dan[a]E
- [a]E-catenin (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Exhibits actin filament binding activity and cadherin binding activity. Involved in tissue homeostasis. Localizes to several cellular components, including adherens junction; catenin complex; and microvillus. Human ortholog(s) of this gene implicated in patterned macular dystrophy 2. Orthologous to human CTNNA1 (catenin alpha 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:76830 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| patterned macular dystrophy 2 | Alliance | Macular dystrophy, patterned, 2 | 608970 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha-catenin | Alpha-catenin/vinculin-like superfamily | Vinculin/alpha-catenin | Vinculin, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:Q9PVF8
|
907 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ctnna1-201
(1)
|
Ensembl | 3,734 nt |
Interactions and Pathways
No data available
Plasmids