Gene
ldha
- ID
- ZDB-GENE-991026-5
- Name
- lactate dehydrogenase A4
- Symbol
- ldha Nomenclature History
- Previous Names
-
- ldha1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have L-lactate dehydrogenase activity. Involved in response to hypoxia. Predicted to localize to cytoplasm. Is expressed in cardiovascular system; gill; muscle; and nervous system. Orthologous to several human genes including LDHA (lactate dehydrogenase A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 28 figures from 16 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55215 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Glycogen storage disease XI | 612933 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR018177 | L-lactate dehydrogenase, active site |
| Domain | IPR001236 | Lactate/malate dehydrogenase, N-terminal |
| Domain | IPR022383 | Lactate/malate dehydrogenase, C-terminal |
| Family | IPR001557 | L-lactate/malate dehydrogenase |
| Family | IPR011304 | L-lactate dehydrogenase |
| Homologous_superfamily | IPR015955 | Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal |
| Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal | Lactate/malate dehydrogenase, C-terminal | Lactate/malate dehydrogenase, N-terminal | L-lactate dehydrogenase | L-lactate dehydrogenase, active site | L-lactate/malate dehydrogenase | NAD(P)-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9PVK5
|
333 |
Interactions and Pathways
No data available
Plasmids
No data available