Gene

gsk3ab

ID
ZDB-GENE-990714-3
Name
glycogen synthase kinase 3 alpha b
Symbol
gsk3ab Nomenclature History
Previous Names
  • GSK-3[a] (1)
  • gsk3a
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Involved in cardiac muscle cell development; dorsal/ventral pattern formation; and heart looping. Predicted to localize to axon; cytosol; and nucleus. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Orthologous to human GSK3A (glycogen synthase kinase 3 alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gsk3ab Human Ortholog
No data available
Associated With gsk3ab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR039192 Glycogen synthase kinase 3, catalytic domain
Family IPR050591 Glycogen Synthase Kinase-3
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Glycogen Synthase Kinase-3 Glycogen synthase kinase 3, catalytic domain Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:Q9YH61 440
UniProtKB:A0A8M3AQC2 435
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
aberrant processed transcript gsk3ab-203 (1) Ensembl 576 nt
mRNA gsk3ab-201 (1) Ensembl 2,971 nt
ncRNA gsk3ab-003 (1) Ensembl 901 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations