Gene
tle3b
- ID
- ZDB-GENE-990415-85
- Name
- TLE family member 3, transcriptional corepressor b
- Symbol
- tle3b Nomenclature History
- Previous Names
-
- fi28a02
- fj62f10
- grg3 (1)
- gro1
- gro3
- wu:fi28a02
- wu:fj62f10
- zfgro1
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable transcription corepressor activity. Acts upstream of or within myeloid cell differentiation. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including axis; head; mesoderm; pleuroperitoneal region; and unfertilized egg. Orthologous to human TLE3 (TLE family member 3, transcriptional corepressor).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 11 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu137 (18 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR019775 | WD40 repeat, conserved site |
Domain | IPR005617 | Groucho/TLE, N-terminal Q-rich domain |
Family | IPR009146 | Groucho/transducin-like enhancer |
Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
Protein | Length | Groucho/TLE, N-terminal Q-rich domain | Groucho/transducin-like enhancer | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:A0A8M3B166
|
781 | ||||||
UniProtKB:A0A8M3AU86
|
770 | ||||||
UniProtKB:A0A8M3AU69
|
782 | ||||||
UniProtKB:A0A8M2BG40
|
770 | ||||||
UniProtKB:A0A8M3AU78
|
760 | ||||||
UniProtKB:O13168
|
771 | ||||||
UniProtKB:A0A8M3AU75
|
780 | ||||||
UniProtKB:A0A8M3B444
|
760 | ||||||
UniProtKB:A0A8M3BB05
|
761 | ||||||
UniProtKB:A0A8M3BB02
|
781 | ||||||
UniProtKB:A0A8M3B441
|
771 | ||||||
UniProtKB:A0A8M3AU81
|
781 | ||||||
UniProtKB:A0A8M3B175
|
759 |
Interactions and Pathways
No data available
Plasmids
No data available