Gene

hoxa11b

ID
ZDB-GENE-990415-4
Name
homeobox A11b
Symbol
hoxa11b Nomenclature History
Previous Names
  • Hoxa-11
  • hoxa11
  • im:7142641
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have sequence-specific DNA binding activity. Predicted to be involved in multicellular organism development and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in radioulnar synostosis. Is expressed in several structures, including central nervous system; chondroblast; mesenchyme; pectoral fin bud; and pectoral fin field. Orthologous to human HOXA11 (homeobox A11).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hoxa11b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Radioulnar synostosis with amegakaryocytic thrombocytopenia 1 605432
Associated With hoxa11b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR020479 Homeodomain, metazoa
Domain IPR021918 Domain of unknown function DUF3528, homeobox protein, eukaryotic
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Domain of unknown function DUF3528, homeobox protein, eukaryotic Homedomain-like superfamily Homeobox, conserved site Homeodomain Homeodomain, metazoa
UniProtKB:Q9DDU1 283
UniProtKB:B3DHW9 283
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hoxa11b-201 (1) Ensembl 1,878 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations