Gene
hoxa11b
- ID
- ZDB-GENE-990415-4
- Name
- homeobox A11b
- Symbol
- hoxa11b Nomenclature History
- Previous Names
-
- Hoxa-11
- hoxa11
- im:7142641
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in embryonic skeletal joint morphogenesis and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; chondroblast; mesenchyme; pectoral fin bud; and pectoral fin field. Human ortholog(s) of this gene implicated in radioulnar synostosis. Orthologous to human HOXA11 (homeobox A11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7142641 (1 image)
- eu331 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Radioulnar synostosis with amegakaryocytic thrombocytopenia 1 | 605432 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Domain of unknown function DUF3528, homeobox protein, eukaryotic | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|
|
UniProtKB:Q9DDU1
|
283 | |||||
|
UniProtKB:B3DHW9
|
283 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hoxa11b-201
(1)
|
Ensembl | 1,878 nt |
Interactions and Pathways
No data available
Plasmids