Gene

csnk2a1

ID

ZDB-GENE-990415-27

Name

casein kinase 2, alpha 1 polypeptide

Symbol

csnk2a1 Nomenclature History

Previous Names

ck2a1
ck2 alpha
wu:fi38e04 (1)
wu:fi38h03 (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in peptidyl-threonine phosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be part of protein kinase CK2 complex. Predicted to be active in cytosol and nucleus. Orthologous to several human genes including CSNK2A1 (casein kinase 2 alpha 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55460 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With csnk2a1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Okur-Chung neurodevelopmental syndrome	617062

Associated With csnk2a1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Family	IPR045216	Casein Kinase 2, subunit alpha
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily

Domain Details Per Protein

Protein	Length	Casein Kinase 2, subunit alpha	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site
UniProtKB:Q803N7 InterPro	395

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	csnk2a1-201 (1) Ensembl	Ensembl	2,629 nt	Select Tool ZFIN BLAST
mRNA	csnk2a1-202 (1) Ensembl	Ensembl	1,252 nt	Select Tool ZFIN BLAST
mRNA	csnk2a1-203 (1) Ensembl	Ensembl	755 nt	Select Tool ZFIN BLAST
mRNA	csnk2a1-204 (1) Ensembl	Ensembl	912 nt	Select Tool ZFIN BLAST
mRNA	csnk2a1-205 (1) Ensembl	Ensembl	1,013 nt	Select Tool ZFIN BLAST
mRNA	csnk2a1-206 (1) Ensembl	Ensembl	4,744 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations