Gene

mapk12a

ID

ZDB-GENE-990415-257

Name

mitogen-activated protein kinase 12a

Symbol

mapk12a Nomenclature History

Previous Names

ERK6 (1)
fa05c12
mapk12
sapk3 (1)
etID309866.18 (1)
wu:fa05c12
zgc:101695

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Predicted to have MAP kinase activity. Predicted to be involved in intracellular signal transduction and regulation of gene expression. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including brain; epidermis; otic vesicle; polster; and pronephric duct. Orthologous to human MAPK12 (mitogen-activated protein kinase 12).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:101695 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mapk12a Human Ortholog

No data available

Associated With mapk12a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR017441	Protein kinase, ATP binding site
Conserved_site	IPR003527	Mitogen-activated protein (MAP) kinase, conserved site
Domain	IPR000719	Protein kinase domain
Family	IPR008352	Mitogen-activated protein (MAP) kinase p38-like
Family	IPR050117	Mitogen-activated protein kinase
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily