Gene
fzd3a
- ID
- ZDB-GENE-990415-225
- Name
- frizzled class receptor 3a
- Symbol
- fzd3a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have Wnt-activated receptor activity and Wnt-protein binding activity. Involved in anterior/posterior axon guidance; commissural neuron axon guidance; and facial nucleus development. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome and schizophrenia. Is expressed in central nervous system; neural plate; neural tube; neurons; and trigeminal ganglion. Orthologous to human FZD3 (frizzled class receptor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu713 (1 image)
- eu1591 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000539 | Frizzled/Smoothened, 7TM |
| Domain | IPR017981 | GPCR, family 2-like, 7TM |
| Domain | IPR020067 | Frizzled domain |
| Domain | IPR041769 | Frizzled 3, cysteine-rich domain |
| Family | IPR015526 | Frizzled/secreted frizzled-related protein |
| Homologous_superfamily | IPR036790 | Frizzled cysteine-rich domain superfamily |
Domain Details Per Protein
| Protein | Length | Frizzled 3, cysteine-rich domain | Frizzled cysteine-rich domain superfamily | Frizzled domain | Frizzled/secreted frizzled-related protein | Frizzled/Smoothened, 7TM | GPCR, family 2-like, 7TM |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5TZ38
|
685 | ||||||
|
UniProtKB:A0A8M2B7P5
|
686 |
Interactions and Pathways
No data available
Plasmids
No data available