Gene
pparda
- ID
- ZDB-GENE-990415-212
- Name
- peroxisome proliferator-activated receptor delta a
- Symbol
- pparda Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Exhibits sequence-specific DNA binding activity. Involved in neural crest cell development and response to activity. Localizes to chromatin. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Is expressed in several structures, including intestine; liver; ovary; pectoral fin; and pharyngeal arch. Orthologous to human PPARD (peroxisome proliferator activated receptor delta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- af342937 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000536 | Nuclear hormone receptor, ligand-binding domain |
| Domain | IPR001628 | Zinc finger, nuclear hormone receptor-type |
| Family | IPR001723 | Nuclear hormone receptor |
| Family | IPR003074 | Peroxisome proliferator-activated receptor |
| Family | IPR003075 | Peroxisome proliferator-activated receptor, beta |
| Family | IPR050234 | Nuclear hormone receptor family NR1 subfamily |
| Homologous_superfamily | IPR013088 | Zinc finger, NHR/GATA-type |
| Homologous_superfamily | IPR035500 | Nuclear hormone receptor-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Nuclear hormone receptor | Nuclear hormone receptor family NR1 subfamily | Nuclear hormone receptor, ligand-binding domain | Nuclear hormone receptor-like domain superfamily | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor, beta | Zinc finger, NHR/GATA-type | Zinc finger, nuclear hormone receptor-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F8W3D2
|
496 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pparda-201
(1)
|
Ensembl | 1,419 nt | ||
| mRNA |
pparda-202
(1)
|
Ensembl | 1,735 nt |
Interactions and Pathways
No data available
Plasmids
No data available