Gene
pes
- ID
- ZDB-GENE-990415-206
- Name
- pescadillo
- Symbol
- pes Nomenclature History
- Previous Names
-
- etID309792.5 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have ribonucleoprotein complex binding activity. Involved in exocrine pancreas development; oligodendrocyte differentiation; and regulation of cell cycle. Predicted to localize to PeBoW complex; nucleoplasm; and preribosome, large subunit precursor. Used to study Shwachman-Diamond syndrome. Is expressed in several structures, including alar plate midbrain region; digestive system; liver primordium; musculature system; and nervous system. Orthologous to human PES1 (pescadillo ribosomal biogenesis factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56654 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Shwachman-Diamond syndrome | peshi2Tg/hi2Tg | standard conditions | Provost et al., 2012 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BRCT domain | BRCT domain superfamily | Pescadillo |
|---|---|---|---|---|
|
UniProtKB:P79741
|
583 |
Interactions and Pathways
No data available
Plasmids
No data available