Gene
ntn1b
- ID
- ZDB-GENE-990415-168
- Name
- netrin 1b
- Symbol
- ntn1b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Involved in generation of neurons. Predicted to localize to basement membrane. Human ortholog(s) of this gene implicated in congenital mirror movement disorder. Is expressed in several structures, including central nervous system; forebrain neural rod; head; hypochord; and neural plate. Orthologous to human NTN1 (netrin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 25 figures from 18 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zhang et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Mirror movements 4 | 618264 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001134 | Netrin domain |
| Domain | IPR002049 | Laminin-type EGF domain |
| Domain | IPR008211 | Laminin, N-terminal |
| Domain | IPR018933 | Netrin module, non-TIMP type |
| Family | IPR050440 | Laminin/Netrin Extracellular Matrix |
| Homologous_superfamily | IPR008979 | Galactose-binding-like domain superfamily |
| Homologous_superfamily | IPR008993 | Tissue inhibitor of metalloproteinases-like, OB-fold |
Domain Details Per Protein
| Protein | Length | Galactose-binding-like domain superfamily | Laminin/Netrin Extracellular Matrix | Laminin, N-terminal | Laminin-type EGF domain | Netrin domain | Netrin module, non-TIMP type | Tissue inhibitor of metalloproteinases-like, OB-fold |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QUK5
|
602 | |||||||
|
UniProtKB:O42203
|
602 |
Interactions and Pathways
Plasmids
No data available