Gene

hoxd13a

ID

ZDB-GENE-990415-119

Name

homeobox D13a

Symbol

hoxd13a Nomenclature History

Previous Names

hoxd-13
hoxd13
zgc:110511

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have sequence-specific DNA binding activity. Predicted to be involved in multicellular organism development and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in brachydactyly (multiple); brachydactyly-syndactyly syndrome; clubfoot; and cryptorchidism. Is expressed in several structures, including cloaca; mesenchyme; pectoral fin bud; periderm; and tail bud. Orthologous to human HOXD13 (homeobox D13).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

23 figures from 14 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

eu794 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hoxd13a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
brachydactyly type D	Alliance	Brachydactyly, type D	113200
brachydactyly type E1	Alliance	Brachydactyly, type E	113300
brachydactyly-syndactyly syndrome	Alliance	?Brachydactyly-syndactyly syndrome	610713
syndactyly type 5	Alliance	Syndactyly, type V	186300
synpolydactyly	Alliance	Synpolydactyly 1	186000

Associated With hoxd13a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017970	Homeobox, conserved site
Domain	IPR001356	Homeodomain
Family	IPR051003	Anterior-posterior axis regulatory homeobox
Homologous_superfamily	IPR009057	Homedomain-like superfamily