Gene
snap25a
- ID
- ZDB-GENE-980526-468
- Name
- synaptosome associated protein 25a
- Symbol
- snap25a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have SNAP receptor activity and syntaxin binding activity. Involved in locomotory behavior and mitotic cytokinesis. Localizes to plasma membrane. Predicted to colocalize with BLOC-1 complex. Human ortholog(s) of this gene implicated in Down syndrome and congenital myasthenic syndrome 18. Is expressed in nervous system and optic vesicle. Orthologous to human SNAP25 (synaptosome associated protein 25).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 19 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73063 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Moravec et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital myasthenic syndrome 18 | Alliance | ?Myasthenic syndrome, congenital, 18 | 616330 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | SNAP-25 domain | SNAP25, N-terminal SNARE motif, chordates | Target SNARE coiled-coil homology domain |
|---|---|---|---|---|
|
UniProtKB:Q5TZ66
|
204 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
snap25a-201
(1)
|
Ensembl | 2,455 nt | ||
| mRNA |
snap25a-202
(1)
|
Ensembl | 2,147 nt | ||
| mRNA |
snap25a-204
(1)
|
Ensembl | 659 nt | ||
| ncRNA |
snap25a-003
(1)
|
Ensembl | 441 nt |
Interactions and Pathways
No data available
Plasmids
No data available