Gene
snap25b
- ID
- ZDB-GENE-980526-392
- Name
- synaptosome associated protein 25b
- Symbol
- snap25b Nomenclature History
- Previous Names
-
- snap25.2 (1)
- wu:fj33h05
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to have SNAP receptor activity and syntaxin binding activity. Involved in clustering of voltage-gated sodium channels and locomotory behavior. Predicted to colocalize with BLOC-1 complex. Human ortholog(s) of this gene implicated in Down syndrome and congenital myasthenic syndrome 18. Is expressed in nervous system. Orthologous to human SNAP25 (synaptosome associated protein 25).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 17 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73101 (13 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Moravec et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital myasthenic syndrome 18 | Alliance | ?Myasthenic syndrome, congenital, 18 | 616330 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | SNAP-25 domain | SNAP25, N-terminal SNARE motif, chordates | Target SNARE coiled-coil homology domain |
|---|---|---|---|---|
|
UniProtKB:Q6PC54
|
203 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
snap25b-201
(1)
|
Ensembl | 1,582 nt | ||
| mRNA |
snap25b-202
(1)
|
Ensembl | 609 nt | ||
| mRNA |
snap25b-203
(1)
|
Ensembl | 801 nt |
Interactions and Pathways
No data available
Plasmids
No data available